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DeCS
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Descriptor English:
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Cytochrome P-450 CYP2E1
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Descriptor Spanish:
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Citocromo P-450 CYP2E1
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Descriptor Portuguese:
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Citocromo P-450 CYP2E1
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Synonyms English:
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CYP2E1
Dimethylnitrosamine N-Demethylase
4-Nitrophenol-2-Hydroxylase
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Tree Number:
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D08.244.453.040.972
D08.811.682.662.582.338
D08.811.682.690.708.170.040.777
D12.776.422.220.453.040.944
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Definition English:
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An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include alcohol; NITROSAMINES; BENZENE; URETHANE; and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse. |
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Indexing Annotation English:
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do not confuse with other cytochrome P-450 CYP's
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History Note English:
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97; was DIMETHYLNITROSAMIME N-DEMETHYLASE (NM) 1972-96 & was 4-NITROPHENOL-2-HYDROXYLASE (NM) 1984-96
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Allowable Qualifiers English:
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Record Number:
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33012
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Unique Identifier:
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D019392
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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